Oxidative Stress and Hemodynamics in Heart Failure

Why are heart failure patients exercise intolerant? Is it due to oxidative stress? In our latest podcast, Editor in Chief William Stanley talks with first author Melissa Witman (University of Utah) about her study that assessed the impact of an “antioxidant cocktail” on central and peripheral hemodynamics during exercise in heart failure patients. Carlos Negrao (University of Sao Paulo) lends his expert opinion in this lively conversation. Listen and learn.

Melissa A. H. Witman, John McDaniel, Anette S. Fjeldstad, Stephen J. Ives, Jia Zhao, Jose N. Nativi, Josef Stehlik, D. Walter Wray, and Russell S. Richardson A Differing Role of Oxidative Stress in the Regulation of Central and Peripheral Hemodynamics during Exercise in Heart Failure Am J Physiol Heart Circ Physiol, published online September 7, 2012, doi: 10.1152/ajpheart.00568.2012.

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Gene and Cytokine Therapy for Heart Failure

The Editors of AJP-Heart and Circulatory Physiology are excited to present our first ever podcast in both English and Japanese! Associate Editor Masafumi Kitakaze interviews lead author Toshio Nagai (Chiba University) and Editorial Board member Takashi Matsui (University of Hawaii) about the new Review article by Nagai and Komuro on cutting-edge research involving gene and cytokine therapies for heart failure. We cover everything from the molecular level to clinical trials, in two languages!

Toshio Nagai and Issei Komuro Gene and cytokine therapy for heart failure: molecular mechanisms in the improvement of cardiac function Am J Physiol Heart Circ Physiol, published online July 9, 2012, doi: 10.1152/ajpheart.00130.2012.

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JAPANESE VERSION: Gene and Cytokine Therapy for Heart Failure

Listen to our Japanese language podcast on the Review article by Toshio Nagai and Issei Komuro.

Toshio Nagai and Issei Komuro Gene and cytokine therapy for heart failure: molecular mechanisms in the improvement of cardiac function Am J Physiol Heart Circ Physiol, published online July 9, 2012, doi: 10.1152/ajpheart.00130.2012.

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