In our latest podcast we explore the connections between the sarcoplasmic reticulum and the mitochondria within calcium regulation during signaling contractile function and regulation of mitochondrial metabolism. Associate Editor Gary Lopaschuk interviews senior author Gyorgy Csordas (Thomas Jefferson University) and leading expert Pal Pacher (National Institutes of Health), seeking to explore a central question in the work by Garcia-Perez et al—how are the SR and the mitochondria communicating with each other?

Cecilia Garcia-Perez, Timothy G. Schneider, Gyorgy Hajnoczky, and Gyorgy Csordas. Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points. Am J Physiol Heart Circ Physiol, published online ahead of print August 19, 2011, doi:10.1152/ajpheart.00397.2011.