BH4 and Vascular Function in Women

What's the problem with arterial function following menopause? Listen as Editor in Chief William Stanley, senior author Kerrie Moreau (University of Colorado Denver), and leading women’s health expert Virginia Miller (Mayo Clinic) engage in a lively conversation about the latest clinical study by Moreau et al on the role of estrogen and uncoupled nitric oxide synthase in arterial stiffening in post-menopausal women. Can early intervention with estrogen combat accelerated vascular aging after menopause?

Kerrie L Moreau, Amie Meditz, Kevin Deane, Wendy M. Kohrt. Tetrahydrobiopterin Improves Endothelial Function and Decreases Arterial Stiffness in Estrogen-Deficient Postmenopausal Women Am J Physiol Heart Circ Physiol, published ahead of print January 13, 2012, doi:10.1152/ajpheart.01065.2011.