Diet, Sex and Exercise in Mice

Do you need to change your New Year’s dieting resolution? Maybe…according to a new study by Konhilas et al, who looked at the trifecta of soy-based versus casein-based diets, exercise, and sex differences in mice. In this engaging new podcast, Deputy Editor Merry L. Lindsey (University of Mississippi Medical Center) interviews lead author John Konhilas (University of Arizona) and expert Ganesh Halade (University of Alabama at Birmingham) about the complex work by Konhilas and colleagues which layered sex dimorphisms in exercise ability, over adaptation to disease and different elements of diet. Did the authors' waterfall of experiments show that diet and sex interact in an overall response to exercise? Listen now.

John P. Konhilas, Hao Chen, Elizabeth D. Luczak, Laurel A. McKee, Jessica Regan, Peter A. Watson, Brian L. Stauffer, Zain I. Khalpey, Timothy A. McKinsey, Todd R. Horn, Bonnie LaFleur, Leslie A. Leinwand Diet and sex modify exercise and cardiac adaptation in the mouse Am J Physiol Heart Circ Physiol, published January 15, 2015. DOI: 10.1152/ajpheart.00532.2014.