Catalase Overexpression Prevents Mechanical Changes in Abdominal Aortic Aneurysm Formation

Biomedical engineering, animal models of human disease, and potential long-term public health risk factors converge in our latest podcast on the article by Maiellaro-Rafferty et al. Listen as Associate Editor Ivor Benjamin, senior author W. Robert Taylor (Emory University), and leading expert Neal Weintraub (University of Cincinnati) discuss preventing the pathological mechanical changes underlying abdominal aortic aneurysm formation.

Kathryn Maiellaro-Rafferty, Daiana Weiss, Giji Joseph, William Wan, Rudolph L. Gleason, Jr., and W Robert Taylor.Catalase overexpression in aortic smooth muscle prevents pathological mechanical changes underlying abdominal aortic aneurysm formation Am J Physiol Heart Circ Physiol, published online ahead of print May 6, 2011; doi:10.1152/ajpheart.00040.2011.

00:0000:00

Autonomic Regulation of Heart in Spontaneous Hydronephrosis

A cautionary tale for cardiovascular researchers unfolds as Associate Editor Nancy Kanagy talks with authors Debra Diz (Wake Forest University) and Amy Arnold (Vanderbilt University), as well as leading expert Karie Scrogin (Loyola University Chicago), about spontaneous hydronephrosis which this study reveals is associated with decreased baroreflex sensitivity. What presents as a very common, and apparently benign, renal abnormality appears to cause a potential complication in central regulation of blood pressure.

Amy C. Arnold, Hossam A. Shaltout, Shea Gilliam-Davis, Nancy D. Kock, and Debra I. Diz. Autonomic Regulation of Heart in Spontaneous Hydronephrosis Am J Physiol Heart Circ Physiol, published ahead of print April 1, 2011; doi:10.1152/ajpheart.01263.2010.

00:0000:00