AJP-Heart and Circulatory Physiology Podcasts

Update on Hormone Therapy Trials

December 14, 2017

Did the publication of the Women’s Health Initiative (WHI) in 2002 lead to assumptions that may prevent menopausal women from being properly treated? Listen to this enlightening conversation as Editor in Chief Dr. Irving H. Zucker (University of Nebraska Medical Center) interviews senior author Virginia M. Miller (Mayo Clinic College of Medicine) and content expert Barbara Alexander (University of Mississippi) about the new review article by Miller and Harman aimed at understanding the controversies surrounding the WHI and menopausal hormone therapy. This engaging podcast provides a primer on the WHI, confronts the dangers of using imprecise terminology (conjugated equine estrogen compared to 17β-estradiol), and shines a light on the still-evolving study of menopausal hormone therapy. Do the limitations of the Women’s Health Initiative still have repercussions for the daily lives of menopausal women some 15 years post-publication? Listen now.


Virginia M. Miller and S. Mitchell Harman An update on hormone therapy in postmenopausal women: mini-review for the basic scientist  Am J Physiol Heart Circ Physiol, published November 1, 2017. DOI: 10.1152/ajpheart.00383.2017

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